Serum miR-125a-5p and CCL17 Upregulated in Chronic Spontaneous Urticaria and Correlated with Treatment Response
نویسندگان
چکیده
منابع مشابه
بیان miR-125a-3p و miR-125a-5p در بیماران مبتلا به نئوپلاسم‌های میلوپرولیفراتیو
چکیده سابقه و هدف تغییر بیان میکرو RNA می‌تواند باعث شروع و پیشرفت سرطان شود. هدف از مطالعه حاضر، بررسی میزان بیان miR-125a و ارتباط آن با JAK2 allele burden و یافته‌های آزمایشگاهی در بیماران مبتلا به نئوپلاسم‌های میلوپرولیفراتیو شامل پلی‌سیتمی ورا (PV) و ترومبوسیتمی اساسی(ET) بود. مواد و روش‌ها مطالعه حاضر از نوع تجربی بود. در مجموع 40 بیمار مبتلا به PV و ET در زمان تشخیص مورد بررسی قرار گرف...
متن کاملEvaluation of the utility of autologous serum skin test and the efficacy of autologous serum therapy in chronic spontaneous urticaria
Background: Autologous serum skin test (ASST) evaluates the presence of any serum histamine-releasing factors and histamine-releasing autoantibodies. Autologous serum therapy (AST) is a therapy in which repeated injections of autologous serum are administered intramuscularly for treatment of chronicspontaneous urticaria (CSU). The aim of this study is to evaluate the advantages and compare the ...
متن کاملTreatment of Chronic Spontaneous Urticaria
Chronic spontaneous urticaria is defined as persistent symptoms of urticaria for 6 weeks or more. It is associated with autoimmunity in approximately 45 percent of patients. Therapy is often difficult however the initial approach should employ high-dose non-sedating antihistamines; 4-6 tablets/day may be necessary. It has been shown that the response to 4 tablets/day exceeds 3, and exceeds 2, w...
متن کاملChronic Spontaneous Urticaria: Pathogenesis and Treatment Considerations
The treatment of chronic spontaneous urticaria begins with antihistamines; however, the dose required typically exceeds that recommended for allergic rhinitis. Second-generation, relatively non-sedating H₁-receptor blockers are typically employed up to 4 times a day. First-generation antihistamines, such as hydroxyzine or diphenhydramine (Atarax or Benadryl), were employed similarly in the past...
متن کاملSerum miR-125a-5p, miR-145 and miR-146a as diagnostic biomarkers in non-small cell lung cancer.
BACKGROUND Lung cancer is becoming the leading cause of cancer-related deaths with high mortality worldwide and in China as well. Non-small-cell lung cancer (NSCLC) is the most common type of lung cancer accounting for approximately 85% of all cases. Over 70% of cases are at loco-regionally advanced stages or have distant metastasis at the time of presentation with subsequently poor prognosis. ...
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ژورنال
عنوان ژورنال: Acta Dermato Venereologica
سال: 2019
ISSN: 0001-5555
DOI: 10.2340/00015555-3149